Factory Spot Astaxanthin

Astaxanthin, hu ua ASTA, tseem hu ua astaxanthin hauv Hong Kong thiab Taiwan) yog hom xiav xim uas tuaj yeem muab cov ntses ornamental, salmon, cws thiab flamingos liab. Nws cov qauv tshuaj zoo ib yam li beta-carotene. Astaxanthin yog ib tug tswv cuab ntawm pawg carotenoid. Nws kuj yog cov khoom lag luam siab tshaj plaws ntawm carotenoid synthesis, -carotene, lutein, canthaxanthin, lycopene, thiab lwm yam yog cov khoom nruab nrab ntawm carotenoid synthesis, yog li nyob rau hauv qhov xwm txheej, astaxanthin muaj zog Antioxidant.

Astaxanthin yog tsim los ntawm algae, kab mob thiab phytoplankton. Qee cov tsiaj hauv dej, suav nrog crustaceans xws li cws thiab crabs, noj cov algae thiab plankton thiab khaws cov xim hauv lawv cov plhaub, ua rau lawv pom liab. Cov ntses no, nyob rau hauv lem, yog preyed los ntawm ntses (salmon, trout, galley) thiab noog (flamingos, ibis), uas ces khaws cov xim nyob rau hauv lawv daim tawv nqaij thiab fatty ntaub so ntswg. Qhov no yog vim li cas ntses salmon thiab lwm yam tsiaj tshwm liab. Tus xibfwb ntawm Huazhong Agricultural University kuj tau tshawb fawb thiab paub tseeb tias cov xim liab ntawm cov qe liab-core duck qe kuj yog ntuj astaxanthin.

Ntuj astaxanthin yog qhov muaj zog tshaj plaws antioxidant pom nyob rau hauv cov xwm kom deb li deb, thiab nws cov kev ua antioxidant deb tshaj li cov antioxidants uas twb muaj lawm.

Lub npe tshuaj: 3,3′-dihydroxy-4,4′-diketo-, ′-carotene, pigment Aj067-69 CAS No: 472-61-7, molecular formula C40H52O4, [molecular hnyav] 596 86

Nws lub peev xwm los tshem tawm cov dawb radicals yog: 1000 npaug ntawm ntuj VE, 10 npaug ntawm ntuj -carotene, 17 npaug ntawm cov txiv hmab txiv ntoo, 200 npaug ntawm lutein, 150 npaug ntawm OPC, 60 npaug ntawm coenzyme Q10, tshuaj yej polyphenols 200 npaug ntawm lycopene thiab 7x ntawm lycopene.

Tsuas yog algae, poov xab thiab kab mob tuaj yeem tsim cov astaxanthin ntuj, thiab cov tsiaj siab dua tsis tuaj yeem hloov cov qauv tshuaj no. Ntuj astaxanthin kuj muaj qhov pom tseeb tias nws tsuas yog carotenoid uas tuaj yeem dhau los ntawm cov hlab ntsha-hlwb barrier.

Tam sim no, kev tsim khoom ntawm astaxanthin muaj ob txoj hauv kev: kev tsim cov khoom siv dag zog thiab kev tsim khoom lom neeg. Synthetic astaxanthin tsis tsuas yog kim, tab sis kuj tseem txawv ntawm ntuj astaxanthin nyob rau hauv cov nqe lus ntawm cov qauv, muaj nuj nqi, daim ntawv thov thiab kev nyab xeeb.
Nyob rau hauv cov nqe lus ntawm cov qauv, vim lub optical kev ua ntawm cov hydroxyl pawg (-OH) ntawm ob qhov kawg, astaxanthin muaj 3S-3'S, 3R-3'S, 3R-3'R (tseem hu ua sab laug, haiv neeg, thiab sab xis). 3 yam

Daim ntawv isomeric, uas astaxanthin dag yog qhov sib xyaw ntawm 3 hom qauv astaxanthin (25% sab laug, 25% sab xis, 50% racemated), kev ua haujlwm antioxidant tsawg, thiab ntses salmon thiab lwm yam kab mob ua liaj ua teb Cov astaxanthin hauv lub cev. (feem ntau nyob rau hauv cov qauv trans - 3S-3 S hom) yog txawv kiag li. Poov xab-sourced astaxanthin yog 100% dextrorotatory (3R-3'R) thiab muaj ib feem ntawm kev ua haujlwm antioxidant; cov saum toj no ob qhov chaw ntawm astaxanthin yog tsuas yog siv nyob rau hauv cov xim ntawm cov tsiaj tsis noj thiab cov ntaub ntawv. Tsuas yog astaxanthin los ntawm algal qhov chaw muaj 100% sab laug-tes (3S-3'S) qauv thiab muaj qhov ua haujlwm lom neeg muaj zog tshaj plaws. Tom qab xyoo ntawm kev tshawb fawb los ntawm cov tuam txhab loj xws li CYANOTECH, FUJI, thiab YAMAHA, nws yog siv los ua khoom noj rau tib neeg noj qab haus huv, tshuaj pleev ib ce siab, tshuaj.

1) Hais txog kev ua haujlwm ntawm lub cev, kev ruaj ntseg thiab kev ua haujlwm antioxidant ntawm hluavtaws astaxanthin kuj qis dua li ntawm ntuj astaxanthin. Vim tias pawg hydroxyl (-OH) ntawm ob qho kawg ntawm astaxanthin molecule tuaj yeem ua rau esterified, nws qhov kev ruaj ntseg sib txawv. Ntau tshaj 90% ntawm lub ntuj astaxanthin muaj nyob rau hauv daim ntawv esterified, yog li nws yog qhov ruaj khov. Synthetic astaxanthin muaj nyob rau hauv lub xeev dawb, yog li nws ruaj khov Synthetic astaxanthin yuav tsum tau kos kom ruaj khov. Synthetic astaxanthin tsuas muaj li ntawm 1/4 ntawm cov qauv sab laug, yog li nws cov kev ua haujlwm antioxidant tsuas yog kwv yees li 1/4 ntawm lub ntuj.

2) Nyob rau hauv cov nqe lus ntawm daim ntawv thov, cov nyhuv bioabsorption ntawm dag astaxanthin kuj tseem phem dua li ntawm ntuj astaxanthin. Thaum noj cov concentration tsawg, cov concentration ntawm cov khoom siv dag zog astaxanthin hauv cov ntshav ntawm zaj sawv trout yog qis dua li ntawm ntuj astaxanthin, thiab nws tsis tuaj yeem nqus tau hauv lub cev. Hloov mus rau hauv ib qho kev teeb tsa ntuj, nws cov xim muaj peev xwm thiab muaj zog lom neeg tsawg dua li cov natural astaxanthin nrog tib qhov concentration.

3) Nyob rau hauv cov nqe lus ntawm biosafety, thaum siv tshuaj txhais tau tias los ua ke astaxanthin, nws yuav inevitably qhia impurity chemical tshuaj, xws li unnatural by-products ua thaum lub sij hawm synthesis, uas yuav txo tau nws bioavailability kev nyab xeeb. Yog li ntawd, nws tsis tuaj yeem siv hauv tib neeg kev ua lag luam.

1. Cov khoom noj uas muaj astaxanthin hauv algae

Feem ntau cov algae noj tau muaj astaxanthin zaub mov, marine algae xws li reef membrane, Ulva, kelp, wakame, seaweed, agarose thiab lwm yam. Cov dej tsis qab algae muaj xws li Haematococcus pluvialis, av fungus, thiab zaub zaub. Cov khoom noj uas muaj astaxanthin tsuas yog tsim los ntawm ob peb hom algae thiab plankton, feem ntau tsuas muaj astaxanthin intermediates -carotene, vitamin E, thiab lwm yam.

Ntawm lawv, Haematococcus pluvialis (tam sim no feem ntau ntawm cov tuam txhab tsim khoom tsim ntuj tsim astaxanthin los ntawm cov microalgae no) yog cov kab mob uas muaj astaxanthin ntau tshaj plaws, thiab nws cov ntsiab lus astaxanthin tuaj yeem ncav cuag 3. 0%, lossis ntau dua, lub npe hu ua "cov khoom sib xyaws" ntawm ntuj astaxanthin.

2. Cw cov khoom noj uas muaj astaxanthin (noj astaxanthin los ntawm cov dej hiav txwv thiab cov dej tsis qab ntsev, plankton, thiab lwm yam)

(1). Cov khoom noj uas muaj astaxanthin Freshwater cw: Crayfish (crayfish), cw dej tshiab, cws dej, cov cw nyom, thiab cov cw dej tshiab (cov cw dej tshiab). 2. Cov khoom noj uas muaj astaxanthin Seawater cw: muaj lobster (Suav lobster), hiav txwv cws (liab cws, loj liab cws), prawn (prawn), base cws (sea cws), pipa cws thiab lwm yam cws hiav txwv.

(2). Cw nyob rau hauv dej brackish, xws li cws dawb, thiab lwm yam, tsis muaj teeb meem dab tsi ntawm cws, ntxiv rau cov khoom noj uas muaj astaxanthin raws li tus nqi tseem ceeb, raws li kev tshawb fawb tshawb fawb, cov khoom noj muaj protein ntau ntawm cws suav txog 16-20 %, thiab cov khoom noj muaj txiaj ntsig zoo heev, nws cov nqaij yog mos li ntses, yooj yim zom, tab sis tsis muaj ntxhiab tsw thiab cov pob txha, thiab nplua nuj nyob rau hauv cov zaub mov (xws li calcium, phosphorus, hlau, thiab lwm yam), seawater cw yog kuj nplua nuj nyob rau hauv iodine, uas muaj txiaj ntsig zoo rau tib neeg kev noj qab haus huv.

3. Cov khoom noj uas muaj astaxanthin hauv crabs (astaxanthin kom tsawg yog tib yam li cw)

(1). Crabs 90% ntawm cov khoom noj uas muaj astaxanthin yog cov nqaij nruab deg, thiab cov khoom noj muaj xws li portunus trituberculatus (sea crab), portunus pelagics, blue crab (tseem hu ua daj crab thiab squid), thiab lwm yam.

(2). 10% ntawm cov khoom noj uas muaj astaxanthin hauv crabs yog los ntawm cov dej tshiab. Cov khoom noj uas muaj astaxanthin hauv crabs muaj xws li Suav mitten crabs, tseem hu ua cov plaub hau crabs, crabs, dej crabs, thiab dej ntshiab cov plaub hau crabs (xws li Liangzi Lake, Yangcheng Lake plaub hau crabs, thiab lwm yam) nto moo), thiab lwm yam. Feem ntau, cws thiab Crab cov khoom noj uas muaj astaxanthin muaj 80-100 mg ntawm astaxanthin hauv 1000 grams ntawm cw shells, thiab crayfish zaub mov muaj astaxanthin muaj cov ntsiab lus siab tshaj plaws ntawm astaxanthin ntawm tag nrho cov cw thiab crabs. 1000 grams ntawm cws plhaub muaj li ntawm 800-1000 mg ntawm astaxanthin. Txawm li cas los xij, tshwj tsis yog qee txoj kev ua noj xws li cov nqaij npuas roj, qee qhov ntawm astaxanthin tuaj yeem lim tawm ntawm cov cw thiab crab shells, thiab feem ntau ntawm cov astaxanthin raug muab pov tseg nrog rau cov cw thiab crab shells.

1. Cov nyhuv tiv thaiv ntawm lub qhov muag thiab lub hauv paus paj hlwb

Tib neeg retina thiab lub paj hlwb hauv nruab nrab (lub hlwb) yog nplua nuj nyob rau hauv unsaturated fatty acids thiab yog li ntawd raug rau peroxidative puas tsuaj los ntawm dawb radicals uas ua los ntawm oxidation. Cov kev tshawb fawb tau pom tias astaxanthin tuaj yeem yooj yim dhau los ntawm cov hlab ntsha hauv hlwb thiab cov cell membrane, thiab tuaj yeem tiv thaiv retinal oxidation thiab photoreceptor cell puas, nrog rau kev tiv thaiv lub hauv nruab nrab paj hlwb, tshwj xeeb tshaj yog lub hlwb, yog li muaj txiaj ntsig zoo rau ischemia-regeneration. Perfusion raug mob, txha caj qaum raug mob, Parkinson's syndrome, Alzheimer's syndrome thiab lwm yam kev raug mob hauv nruab nrab paj hlwb. Tshwj xeeb tshaj yog macular degeneration nyhuv yog qhov tseem ceeb tshaj li lutein. US CADAX lub tuam txhab tau siv astaxanthin los ua ib qho tshuaj tiv thaiv kev rov ua mob rov qab tom qab cerebral infarction, thiab nws tau raug tshaj tawm tias nws tau nkag mus rau theem kev sim tshuaj hauv xyoo 2010. Qhov txiaj ntsig loj tshaj plaws yog tias nws yuav tsis ua rau cov coagulation tsis zoo li cov tshuaj antiplatelet.

2. Siv tau los tiv thaiv wrinkle thiab whitening

Cov tawv nqaij muaj peb txheej: epidermis, dermis, thiab subcutaneous rog. Lub dermis muaj collagen, elastin, thiab lwm yam fibers uas ua rau lub cev pob txha uas txhawb cov tawv nqaij. Nws yog cov ntsiab lus no uas ua rau cov tawv nqaij zoo nkauj thiab hluas, thiab cov ntsiab lus tib yam no kuj muaj kev puas tsuaj rau UVA thiab UVB.

Cov kab hluav taws xob ultraviolet tau muab faib ua qhov ntev-yoj ultraviolet UVA thiab luv-yoj ultraviolet UVB. Ntawm lawv, UVA, lub teeb ntev-ntev ultraviolet, tuaj yeem ncav cuag lub dermis vim nws qhov ntev wavelength, feem ntau ua rau collagen thiab elastin, thiab lub cev pob txha txhawb lub epidermis ploj mus, ua rau lub cev tsis sib xws ntawm cov epidermis thiab tsim ntawm daim tawv nqaij wrinkles. , thaum UVB feem ntau ua rau ntawm daim tawv nqaij, ua rau Sunburn los yog deposition ntawm melanin, uas ua rau pob txuv los yog darkens ntawm daim tawv nqaij.

Ultraviolet UV tsim nyob rau hauv situ active oxygen thiab matrix metalloproteinases, uas yog lub hauv paus ua rau wrinkles vim lawv rhuav tshem collagen matrix ntawm lub dermis.

Cov tawv nqaij kho lub cev muaj peev xwm rov tsim kho cov collagen puas lawm, txawm li cas los xij, yog tias cov haujlwm puas tsuaj ntawm cov pa oxygen reactive (ROS) thiab matrix metalloproteinases (NMP) tsis tau tswj tau zoo, lawv yuav txuas ntxiv ua rau cov collagens puas tsuaj, uas yuav ua rau muaj kev cuam tshuam loj. Cov txheej txheem kho ntawm daim tawv nqaij, thaum astaxanthin tuaj yeem ua rau tsis muaj zog ntawm ROS thiab NMP rau dermal collagen thiab elastin, ua kom cov metabolism hauv cov tawv nqaij. Yog tias sab nraud astaxanthin ua ke nrog qhov ncauj astaxanthin, thiab qee cov khoom noj uas muaj collagen ntxiv rau tib lub sijhawm, wrinkles yuav raug kho sai.

Nrhiav qhov tseeb los ntawm qhov tseeb: tso siab rau "elastin" thiab "collagen" nkaus xwb tsis tuaj yeem tshem koj cov ko taw. Cov no tsuas yog cov khoom xyaw xwb, thiab lub zog muaj zog los ntawm cov muaj zog antioxidant astaxanthin.

3. Txhim khu kev tiv thaiv thiab txo kev qaug zog

Astaxanthin tuaj yeem cuam tshuam rau kev tiv thaiv kab mob ntawm cov tsiaj. Nyob rau hauv lub xub ntiag ntawm antigens, nws muaj peev xwm txhawb nqa lub peev xwm ntawm spleen hlwb los tsim cov tshuaj tiv thaiv, txhim khu kev ua haujlwm ntawm T hlwb, thiab txhawb kev tsim cov immunoglobulins hauv lub cev. Astaxanthin tuaj yeem ua rau qee qhov rov ua kom lub cev tsis muaj zog ntawm cov nas muaj hnub nyoog, uas tuaj yeem nce IgM, IgA thiab IgG hauv cov nas mus rau 10mol / L, qhia tias nws tuaj yeem txhim kho qhov tshwj xeeb humoral tiv thaiv kab mob nyob rau theem pib ntawm antigen ntxeem tau. Tsis tas li ntawd, astaxanthin tseem tuaj yeem txhim kho lub peev xwm ntawm cov nas tso tawm interleukin-I thiab cov qog necrosis, uas muaj zog ntau dua li -carotene thiab canthaxanthin. Yog li ntawd, nws tau txiav txim siab tias astaxanthin muaj cov haujlwm muaj zog ntawm inducing cell division thiab muaj lub luag haujlwm tseem ceeb hauv kev tiv thaiv kab mob.