ResveratrolhmoovNws yog inconspicuous thaum xub thawj, tab sis nws tig lub dab tuag duckling mus rau hauv lub swan nrog lub npe nrov "Fabkis paradox" - ib tug loj feem ntawm cov rog nyob rau hauv Fabkis noj, tab sis qhov tshwm sim ntawm cov kab mob plawv yog tsawg heev, thiab tom qab ntawd pom qhov no muaj feem xyuam rau lawv. tus cwj pwm ntawm kev hais txog cawv liab, thiab cov txiv hmab txiv ntoo liab yog ib qho ntawm cov nplua nuj ntawm nws.
Txawm hais tias tom qab ob peb txoj kev tshawb fawb, nws ntseeg tau tias qhov kev tiv thaiv kab mob plawv no yog qhov sib cav, nws qhov kev ua tau zoo hauv kev tu tawv nqaij yog pom tseeb rau txhua tus - resveratrol tau suav nrog hauv "Catalogue of Cosmetic Raw Materials Used" thiab "International Catalog of Cosmetic Raw Materials.
01 Whitening nyhuv
Hauv melanocytes, tyrosine yog catalyzed los ntawm ntau yam enzymes, feem ntau tyrosinase, los tsim melanin, thiab nws thiaj li, ib feem ntawm nws raug xa mus rau stratum corneum rau deposition, ua rau darkening ntawm daim tawv nqaij. Nws inhibits qhov kev ua ntawm tyrosinase, uas tuaj yeem cuam tshuam cov synthesis ntawm melanin, kom ua tiav cov nyhuv ntawm whitening.
Nyob rau tib lub sij hawm, txoj kev tshawb no kuj pom tias nws muaj zog cytotoxic nyhuv ntawm B16 hlwb ntawm high concentrations, thaum nyob rau hauv qis concentrations, lub toxicity ntawm uas yog heev txo, thiab nws tseem muaj thiab VC, Arbutin muaj tib lub whitening nyhuv ntawm siab concentration.
02 Anti-photoaging nyhuv
Cov kab hluav taws xob ultraviolet uas tuaj yeem nkag mus rau qhov chaw thiab ua rau tib neeg cov tawv nqaij puas tsuaj yog UVA thiab UVB. UVA yog qhov ntev-yoj ultraviolet rays. Nws irradiates daim tawv nqaij thiab txhawb txoj kev NF-κB thiab txhawb kev tsim ntawm IL-1, TNF- , thiab MMP-1. Tib lub sijhawm, Tib neeg fibroblasts irradiated nrog UVA tuaj yeem tshaj tawm MMP-1 thiab MMP-3 noob thiab cov proteins. Overexpression ntawm MMPs tuaj yeem ua rau wrinkles, tawv nqaij sagging, thiab dilation ntawm microvessels.
Ntau qhov kev tshawb fawb tau pom tias resveratrol muaj qee yam inhibitory cuam tshuam ntawm NF-κB txoj hauv kev, MMPs, thiab IL-1 hauv kab lis kev cai tib neeg cov tawv nqaij fibroblasts, yog li txo qhov tshwm sim ntawm daim tawv nqaij puas thiab kev laus tom qab UV irradiation.
Kev sim qhia tiasresveratrolhmoovtuaj yeem tiv thaiv photodamage thiab tiv thaiv kev yees duab los ntawm inhibiting IL-1 thiab NF-κB.
