Kuv yuav ua li cas thiaj li nce kuv qib NAD NAD?

Nad +, hu ua Nicotinamide Adenine Dinucleotide, yog coenzyme tam sim no nyob rau hauv tag nrho cov muaj sia, tseem hu ua coenzyme No. 1.
Mitochondria xav tau NAD + los hloov cov as-ham mus rau lub zog (ATP). Cov kev sib txawv ntawm lub cev muaj zog yuav tsum muaj cov protein sib txawv. Nad + tswj kev ua si ntawm cov protein.

NAD + muaj ob lub luag haujlwm dav thiab hauv paus hauv tib neeg lub cev:
1. Tsim lub zog.

NAD + yog qhov tseem ceeb rau kev metabolism hauv xov tooj, pab hloov cov khoom noj mus rau lub zog koj lub cev xav tau ua haujlwm.
2. Cov kev cai ntawm cov txheej txheem cellular.

Raws li ib qho kev txhawb nqa molecule, NAD + ncaj qha cuam tshuam rau ntau yam ntawm cellular kev kho, suav nrog DNA kho, cov neeg tawm, thiab kev tiv thaiv kab mob.

● NAD yog synthesized los ntawm cov hlwb los ntawm lub tsev blocks (ua ntej) ntawm NAD muaj nyob rau hauv kev noj haus.Vitamin B3 (Niacin) thiab Tryptophan yog lub tsev vaj thaiv ntawm NAD.Tsawg cov zaub mov noj ntawm cov ua ntej yog qhov kev pheej hmoo hnyav rau cov qib NAD tsawg.
● NAD tsis lees txais nrog lub hnub nyoog, tejzaum nws vim tias muaj peev xwm tsawg dua los txhawb nqa tshiab NAD thiab rov ua dua tshiab Nad.Cov qib qis NAD tau muaj feem ntau nyob hauv nruab nrab-hnub nyoog thiab cov laus laus dua, thiab qis dua rau menyuam yaus.
● Nad yog tsis txaus nyob rau hauv ib feem ntawm cov neeg mob uas muaj kab mob ntsig txog hnub nyoog.
Theem siab ntawm NAD-degroorading enzymes tej zaum yuav yog lub luag haujlwm rau kev hloov pauv sai thiab qib qis ntawm NAD:Peb qhov tseem ceeb enzymes, cd38, parp, thiab sirtuins, muaj lub zog muaj zog ntawm naad kev ua tsis raws cai. CD38 muaj ntau zog tiv thaiv kab mob ntawm lub plab thiab tej zaum yuav yog tus yuam sij pheej hmoo rau NAD poob rau cov neeg laus.
Nad Nad Lub cev tsis txaus ntseeg tau pom tias muaj qee cov tsev neeg,tawm tswv yim hais tias noob caj noob ces yuav cuam tshuam rau NAD qib,tsawg kawg ib nrab lossis hauv ib co tsev neeg.

Qhov laj thawj tseem ceeb rau NAD + poob qis nrog lub hnub nyoog yog ob txhais. Ua ntej, raws li lub cev muaj hnub nyoog, nws tsim cov nad tsawg +. Thib ob, puas tsuaj los ntawm kev o, oxidative kev nyuaj siab, thiab DNA kev puas tsuaj depletes nad + hauv lub cev. Raws li qhov tshwm sim, ntau cov txheej txheem biological uas vam khom NAD + yog hloov.
Tsawg nad + yog lub hauv paus ntawm ntau cov hnub nyoog muaj teeb meem. Kev txo nyob rau hauv Nad + ua rau poob rau hauv kev noj qab haus huv cell metabolism. Qhov no, nyob rau hauv lem, tuaj yeem ua rau cov cim uas muaj kev sib tw ntawm cov leeg nqaij, muaj peev xwm txo qis, rog, thiab lwm yam. Poob hauv NAD + kuj tau txuas ntxiv rau ntau cov kab mob muaj feem xyuam.
Txij li thaum nad + yog qhov tseem ceeb rau cov cell muaj nuj nqi, tsis muaj ntau lub cev ua haujlwm uas nws tsis cuam tshuam dab tsi. Kev tshawb fawb yog tshawb nrhiav qhov sib txuas ntawm NAD + poob qis thiab kev pom ntawm kev laus ntawm cev ntawm cev. Cov cwj pwm no tau xav tias yog lub siab ntawm kev laus hauv lub cev.
Lub xovtooj ntawm kev laus ntawm kev laus yog:Genomic Insitility, Telome Kev Zoo Siab, Kev Tawm Tsam Tawm Tsam, Mitein ruaj khov), MiteRegulated zoo nkauj, mitoregulated kev sib txuas lus zoo, thiab kho cov kev sib txuas lus hauv tes. Ntawm no yog qhov peb tau paub txog NAD + 'S cuam tshuam rau ntau yam ntawm ob peb lub cev muaj peev xwm ua rau koj lub cev muaj peev xwm ntawm kev laus.
1. Genome Tsis Muaj Peev Xwm
Genome Instability txhais tau hais tias tsis xws luag nyob rau hauv cov txheej txheem uas tswj tau li cas cell faib. Raws li qhov tshwm sim, qhov Genome tau hloov thaum lub sijhawm faib khoom thiab tsis raws nraim cov qauv qub. Thaum DNA tsis tuaj yeem luam tawm kom zoo lossis kho kev puas tsuaj, nws ua rau kev sib hloov hauv cov qauv caj ces.
Ib qho kev txo qis hauv NAD + inhibits lub peev xwm ntawm cov hlwb los faib thiab kho DNA kho.Kev tshawb fawb qhia tau hais tias ntxiv rau NAD + hauv cov nas laus txhim kho lub hlwb 'muaj peev xwm kho tau DNA.
2. Teloere hnav
Txhua chromosome xaus nrog tus tiv thaiv lub zog hu ua lub telomere. Txhua zaus cov cell faib, cov telomeres tau luv dua. Thaum telomeres yog luv heev, cov hlwb tsis tuaj yeem tsim tawm, uas ua rau cov ntaub so ntswg thiab kev tuag. Cov lus qhia luv luv yog txuam nrog ntau cov hnub nyoog ntsig txog cov kab mob ntev.
Qhov ntev thiab muaj nuj nqi ntawm telomeres muaj kev tiv thaiv los ntawm ib tsev neeg ntawm cov protein hu ua sirtuins. Ntawm lawv cov ntau cov haujlwm, sirtuins tswj hwm thiab ncua kev laus ntawm lub cev-thiab lawv vam khom NAD + kom ua haujlwm zoo. Kev kawm tsis ntev los no hauv cov nas ua kom nce nad + tau cuam tshuam nrog kev ua haujlwm sirtin nce ntxiv. Ua kom nce sirtin kev ua haujlwm ruaj khov telomeres, txo cov kev puas tsuaj DNA, thiab txhim kho cov mob telomere-dependent.
3. Cell Counces
Lwm cov txheej txheem kev laus ntawm kev laus yog hu ua cellular senescation. Laus cia txhais tau tias "txheej txheem ntawm tau laus dua." Thaum cov hlwb uas laus thiab tsis muaj zog tuag, koj lub cev tsis muaj zog tiv thaiv lawv ntawm koj lub cev. Senterescent hlwb, ntawm qhov tod tes, yog malfunctioning cell uas tsis tau sib faib tsis yog tab sis tsis tuag thiab nyob hauv lub cev. Lawv sib sau nrog lub hnub nyoog thiab ua rau muaj kev sib raug zoo uas cuam tshuam nrog kev laus.
Kev tshawb fawb tau qhia tias Bog + qib hauv cov nas laus tuaj yeem rov qab ua rau cov leeg qe thiab tiv thaiv kev laus, thiab nce tag nrho lub neej.

Tam sim no muaj peb txoj hauv kev los nce NAD + theem: Ua kom muaj NAD Biosynthetic enzymes thiab inhibition, nad + kev cuam tshuam, lossis ntxiv rau

● Ketone lub cev muaj kev nce qib Nad + theem

Qhov no kuj tseem yog ib txoj hauv kev tseem ceeb ntawm kev thiav / rov qab / rov qab / ntawm cov zaub mov ketogenic. Ketone lub cev txo cov kev tsim cov khoom siv cov pa roj oxygen hauv mitochondria los ntawm kev nce oxidation ntawm Nadh rau NAD +. Cov khoom noj khoom haus Ketogenic txhawb nqa NAD + qib los ntawm cov rog roj plab oxidation thiab cov kua pleev ntshav qab zib. Lwm cov kev tshawb fawb tau pom tias Ketone lub cev tuaj yeem nce Redox Nad + / Nadh piv rau lub hlwb so ntawm cov neeg hluas noj qab nyob zoo. Yog li no, lub xeev cov khoom noj muaj txiaj ntsig pab tiv thaiv kev noj qab haus huv ntawm lub hlwb, thiab cov khoom noj muaj txiaj ntsig ua rau koj lub xeev zoo dua thiab zoo dua.

● Caloric kev txwv (CR)
Caloric kev txwv yog qhov yooj yim thiab pheej yig tshaj plaws los nce nad +, thiab nws muaj lwm cov txiaj ntsig. Muaj ntau txoj kev ntawm Caloric txwv los txhawb qhov nce ntawm NAD +. Lub hauv paus ntsiab lus tseem ceeb yog tias Calorie txo qis dua tso nyiaj ATP, yog li lub cev yuav tshwm sim ntxiv qee qhov kev ntsuas kom rov qab kho dua. Piv txwv li, ua kom cov kev qhia ntawm nicotinamide los txhawb lub NAD + khaws cia Nadh qib tsis ncaj rau NAD + / Nadh piv, thiab ua kom muaj sirtuins. Vim tias Nadh yog cov neeg sib tw inhibitor ntawm Sir2, Nadh txo cov kev sib tw ntawm sirtuins.

Cov khoom noj uas txhawb NAD +
Hauv peb kev noj zaub mov txhua hnub, peb tuaj yeem noj cov khoom noj ntau uas muaj NAD + precursors. Piv txwv li, Tryptophan pom nyob hauv cov zaub mov xws li qaib cov txwv, nqaij qaib, nqaij npuas, nqaij nyug, mutton, thiab qe. Vitamin B3, uas tau ua tau zoo tshaj li tryptophan, yog muaj txiaj ntsig zoo hauv nqaij, ntses thiab cov khoom siv mis nyuj, mackerel, sardines thiab trout. Cheese, yogurt, natto, sauerkraut thiab lwm cov zaub mov fermieted yog nplua nuj nyob rau hauv probiotics thiab b vitamins, uas tuaj yeem txhawb nqa cov khoom nad +.

Yog tias koj xav tau paam vera extract hmoov, thov hu rau peb email:chriswang@sheerherb.com