Lub ntsws yog ib qho tseem ceeb ntawm tib neeg txoj kev ua pa. Nws yog lub luag haujlwm tseem ceeb rau kev sib pauv roj hauv lub cev. Thaum lub ntsws ua haujlwm poob qis, nws yuav tsis tsuas cuam tshuam rau lub ntsws, tab sis kuj cuam tshuam rau lub cev dej metabolism, ntshav ncig, lub cev tsis muaj zog thiab lwm yam haujlwm.
Kev ua haujlwm ntawm lub ntsws tseem ceeb heev, tab sis nws qhov kev poob qis yog ntau dua li peb xav. Lub caij nyoog siab tshaj plaws ntawm lub ntsws loj hlob thiab kev ua haujlwm yog 18-25 xyoo, nws tseem nyob ruaj khov nrog kev hloov me ntsis txog 35 xyoo, thiab maj mam poob tom qab ntawd.
Thaum peb muaj hnub nyoog, peb lub ntsws ua haujlwm poob qis ib xyoos ib zaug, ua rau cov neeg laus muaj kev cuam tshuam rau cov kab mob ua pa. Raws li kev txheeb cais, qhov kev tuag ntawm cov tib neeg muaj hnub nyoog tshaj 80 xyoo yog 20 npaug lossis ntau dua ntawm cov neeg muaj hnub nyoog 50 xyoo.
Ntxiv nrog rau kev laus, nyob rau hauv lub neej niaj hnub, ntau yam sab nraud kuj tseem ua rau lub ntsws nce siab, ua rau nws muaj hnub nyoog sai: xws li haus luam yeeb, smog, chav ua noj fumes, tus kab mob ntxeem tau thiab lwm yam.
NMN yog ib yam khoom tseem ceeb uas muaj dav hauv cov kab mob thiab muaj feem cuam tshuam nrog NAD ntxiv rau cov metabolism. NMN muaj ntau yam kev ua haujlwm ntawm lub cev, suav nrog kev tiv thaiv oxidation, tiv thaiv kab mob, tiv thaiv kev laus, thiab lwm yam, yog li nws tseem ceeb heev rau kev noj qab haus huv ntawm lub ntsws.
Kev sib raug zoo ntawm lub ntsws laus thiab NAD ntxiv yog dab tsi?
NMNyog ib tug precursor rau nicotinamide adenine dinucleotide (NAD ntxiv), ib tug tseem ceeb molecule nyob rau hauv metabolism thiab DNA noj qab haus huv uas tau pom tias yuav txo tau nrog lub hnub nyoog nyob rau hauv ntau hom ntawm tes thiab kabmob, nrog rau lub ntsws. Cov kab mob uas muaj hnub nyoog xws li kab mob plawv, kab mob neurodegenerative, thiab cov kab mob metabolic yog txhua yam cuam tshuam nrog txo NAD ntxiv rau qib.
Lub luag haujlwm tseem ceeb ntawm NMN
• Anti-inflammatory nyhuv ntawm NMN
Inflammation yog ib qho ntawm cov kab mob tseem ceeb ntawm cov kab mob ntsws. Cov lus teb ntev ntev tuaj yeem ua rau kho txoj hlab pa, fibrosis, thiab thaum kawg lub ntsws ua haujlwm poob. NMN tuaj yeem txo qis kev puas tsuaj los ntawm inhibiting qhov inflammatory teb.
● Antioxidant nyhuv ntawm NMN
Oxidative stress yog ib qho tseem ceeb ntawm cov kab mob hauv lub ntsws. Kev ntxhov siab oxidative ntau dhau tuaj yeem ua rau muaj kev puas tsuaj rau cov qauv ntawm tes, ua rau mob ntxiv thiab ua rau lub ntsws ua haujlwm tsis zoo. NMN muaj cov nyhuv antioxidant tseem ceeb thiab tuaj yeem tshem tawm cov dawb radicals ntau dhau hauv lub cev.
● Anti-fibrotic nyhuv ntawm NMN
Pulmonary fibrosis yog ib hom kab mob ntsws uas tshwm sim los ntawm ntau cov fibrous deposition nyob rau hauv lub ntsws parenchyma, nws thiaj li ua rau lub ntsws tsis ua hauj lwm. NMN tau pom tias muaj peev xwm kho tau zoo hauv kev tiv thaiv fibrosis. Cov kev tshawb fawb tau lees paub tias NMN tuaj yeem txo qhov ua kom thiab nthuav dav ntawm lub ntsws fibroblasts los ntawm inhibiting TGF- 1/Smad txoj kev, yog li inhibiting qhov tshwm sim ntawm fibrosis. Cov kev tshawb fawb tau pom tias NMN tuaj yeem dhau los ua cov tshuaj muaj peev xwm nrog cov tshuaj tiv thaiv fibrotic.
● NMNs tswj kev tiv thaiv kab mob
Lub cev tiv thaiv kab mob ua lub luag haujlwm tseem ceeb hauv kev tswj lub ntsws. NMN muaj peev xwm tswj tau lub cev tiv thaiv kab mob thiab tuaj yeem cuam tshuam rau kev ua haujlwm ntawm lub cev tiv thaiv kab mob. Cov kev tshawb fawb tau pom tias NMN tuaj yeem txhim kho lub peev xwm phagocytic ntawm macrophages, ua rau lawv muaj peev xwm tshem tau cov kab mob thiab cov kab mob inflammatory. Nyob rau tib lub sijhawm, NMN tuaj yeem tswj hwm kev ua haujlwm ntawm T hlwb, yog li ntsuas qhov sib piv ntawm Th1 / Th2 hlwb thiab txo qhov mob ntsws. Cov luag haujlwm no hauv kev tswj hwm kev tiv thaiv kab mob ua rau NMN muaj kev thov dav dav hauv kev kho mob ntsws.
